Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 14/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322763 | 1.00 | TACR1 (0.52) | TACR1BCHEACHEBACE1 | |
| SCHEMBL9322742 | 1.00 | TACR1 (0.52) | TACR1BCHEACHEBACE1 | |
| SCHEMBL9322753 | 1.00 | TACR1 (0.52) | TACR1BCHEACHEBACE1 | |
| SCHEMBL9325208 | 0.88 | TACR1 (0.52) | TACR1BCHEACHEBACE1 | |
| SCHEMBL9324143 | 0.88 | TACR1 (0.52) | TACR1BCHEACHEBACE1 | |
| SCHEMBL9325214 | 0.88 | TACR1 (0.52) | TACR1BCHEACHEBACE1 | |
| SCHEMBL9325219 | 0.88 | TACR1 (0.52) | TACR1BCHEACHEBACE1 | |
| SCHEMBL9324119 | 0.88 | TACR1 (0.52) | TACR1BCHEACHEBACE1 | |
| SCHEMBL9325229 | 0.88 | TACR1 (0.52) | TACR1BCHEACHEBACE1 | |
| SCHEMBL9324137 | 0.88 | TACR1 (0.52) | TACR1BCHEACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409931-B1 | QUINUCLIDINE THERAPEUTIC AGENTS | PFIZER (US) | 1994-02-16 | — | — | EP | disclosed |
| US-5162339-A | Substance P Antagonists, Gastrointestinal and Central Nervous System Disorders, Antiinflammatory Agents, Analgesics | PFIZER INC. (US) | 1992-11-10 | — | — | US | disclosed |
| WO-1990005525-A1 | QUINUCLIDINE DERIVATIVES AS SUBSTANCE P ANTAGONISTS | PFIZER INC. (US) | 1990-05-31 | — | — | WO | disclosed |