Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14364967 | 0.85 | MRGPRX1 (0.55) | MRGPRX1ALDH1A1POLB | |
| SCHEMBL2781629 | 0.85 | MRGPRX1 (0.55) | MRGPRX1ALDH1A1POLB | |
| SCHEMBL6135225 | 0.85 | MRGPRX1 (0.55) | MRGPRX1ALDH1A1POLB | |
| SCHEMBL9325051 | 0.78 | MRGPRX1 (0.48) | MRGPRX1ALDH1A1POLB | |
| SCHEMBL9743327 | 0.77 | MRGPRX1 (0.46) | MRGPRX1 | |
| SCHEMBL5078507 | 0.77 | MRGPRX1 (0.49) | MRGPRX1 | |
| SCHEMBL8802582 | 0.76 | MRGPRX1 (0.43) | MRGPRX1 | |
| Benzylamine SCHEMBL28553128 | 0.76 | MRGPRX1 (0.55) | MRGPRX1 | |
| SCHEMBL9322829 | 0.76 | MRGPRX1 (0.47) | MRGPRX1ALDH1A1POLB | |
| SCHEMBL700103 | 0.76 | MRGPRX1 (0.46) | MRGPRX1CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409931-B1 | QUINUCLIDINE THERAPEUTIC AGENTS | PFIZER (US) | 1994-02-16 | — | — | EP | disclosed |
| US-5162339-A | Substance P Antagonists, Gastrointestinal and Central Nervous System Disorders, Antiinflammatory Agents, Analgesics | PFIZER INC. (US) | 1992-11-10 | — | — | US | disclosed |
| WO-1990005525-A1 | QUINUCLIDINE DERIVATIVES AS SUBSTANCE P ANTAGONISTS | PFIZER INC. (US) | 1990-05-31 | — | — | WO | disclosed |