Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Butyrolactone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyrolactone SCHEMBL1271043 | 0.97 | CA1 (0.82) | — | |
| Butyrolactone SCHEMBL29433925 | 0.97 | — | — | |
| SCHEMBL19638361 | 0.97 | CA1 (0.82) | — | |
| Butyrolactone SCHEMBL13481 | 0.97 | — | — | |
| Butyrolactone SCHEMBL27720055 | 0.97 | CA1 (0.82) | — | |
| Butyrolactone SCHEMBL9421121 | 0.97 | — | — | |
| Butyrolactone SCHEMBL15020456 | 0.94 | — | — | |
| Butyrolactone SCHEMBL5387579 | 0.94 | — | — | |
| Butyrolactone SCHEMBL31403367 | 0.94 | — | — | |
| Butyrolactone SCHEMBL8194800 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107973733-B | Method for preparing selenomethionine | 四川新一美生物科技有限公司 | 2020-04-17 | — | — | CN | claimed |
| CN-116829532-A | Substituted cyclohexane carboxamides, their preparation and their therapeutic use | 赛诺菲 | 2023-09-29 | — | — | CN | disclosed |
| CN-108630979-B | Secondary battery based on calcium ions and preparation method thereof | 深圳先进技术研究院 | 2021-06-15 | — | — | CN | disclosed |
| CN-108470908-B | Secondary battery and preparation method thereof | 深圳先进技术研究院 | 2021-02-09 | — | — | CN | disclosed |
| CN-107221443-B | Sodium ion hybrid super capacitor and preparation method thereof | 深圳中科瑞能实业有限公司 | 2020-02-11 | — | — | CN | disclosed |
| US-20130022628-A1 | ACYL PSEUDOPEPTIDES WHICH CARRY A FUNCTIONALIZED AUXILIARY ARM | OM PHARMA (CH) | 2013-01-24 | — | — | US | disclosed |
| EP-2448930-A1 | COVALENT INHIBITION OF BACTERIAL QUORUM SENSING | The National Institute for Biotechnology in the Negev Ltd. (IL) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011001419-A1 | COVALENT INHIBITION OF BACTERIAL QUORUM SENSING | NATIONAL INSTITUTE FOR BIOTECHNOLOGY IN THE NEGEV (IL) | 2011-01-06 | — | — | WO | disclosed |
| WO-2008060998-A1 | INDOLE SULFONAMIDES AS SFRP-1 MODULATORS | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |
| WO-1999058526-A1 | NOVEL 2,5-PYRIDINEDICARBOXYLIC ACID DERIVATIVES | DONG WHA PHARM. IND. CO., LTD. (KR) | 1999-11-18 | — | — | WO | disclosed |
| EP-0876392-A1 | LACTONE DERIVATIVES OF 17.BETA.-CARBOXY, CARBOTHIO AND AMIDE ANDROSTANE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997024365-A1 | LACTONE DERIVATIVES OF 17.BETA.-CARBOXY, CARBOTHIO AND AMIDE ANDROSTANE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1997-07-10 | — | — | WO | disclosed |