Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 9/20 | 0.51 |
| ▸ | MRGPRX1 | Q96LB2 | 6/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322481 | 0.89 | MRGPRX1 (0.51) | TACR1MRGPRX1CACNA1FCHRM5CACNA1D | |
| SCHEMBL9325071 | 0.83 | TACR1 (0.58) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| SCHEMBL9323405 | 0.82 | TACR1 (0.54) | TACR1 | |
| SCHEMBL9767395 | 0.81 | TACR1 (0.53) | TACR1MRGPRX1 | |
| SCHEMBL9323184 | 0.81 | TACR1 (0.53) | TACR1 | |
| SCHEMBL9322825 | 0.81 | TACR1 (0.55) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| SCHEMBL9322973 | 0.79 | TACR1 (0.60) | TACR1MRGPRX1CACNA1FCHRM5CACNA1D | |
| SCHEMBL9325144 | 0.78 | TACR1 (0.52) | TACR1 | |
| SCHEMBL9322681 | 0.78 | TACR1 (0.61) | TACR1MRGPRX1CACNA1FCHRM5CACNA1D | |
| SCHEMBL9324225 | 0.78 | TACR1 (0.55) | TACR1MRGPRX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409931-B1 | QUINUCLIDINE THERAPEUTIC AGENTS | PFIZER (US) | 1994-02-16 | — | — | EP | disclosed |
| US-5162339-A | Substance P Antagonists, Gastrointestinal and Central Nervous System Disorders, Antiinflammatory Agents, Analgesics | PFIZER INC. (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0409931-A1 | QUINUCLIDINE THERAPEUTIC AGENTS. | PFIZER (US) | 1991-01-30 | — | — | EP | disclosed |
| WO-1990005525-A1 | QUINUCLIDINE DERIVATIVES AS SUBSTANCE P ANTAGONISTS | PFIZER INC. (US) | 1990-05-31 | — | — | WO | disclosed |
| WO-1990005729-A1 | QUINUCLIDINE THERAPEUTIC AGENTS | PFIZER INC. (US) | 1990-05-31 | — | — | WO | disclosed |