⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13245191 | 1.00 | — | — | |
| SCHEMBL932292 | 1.00 | — | — | |
| SCHEMBL13245610 | 0.99 | — | — | |
| SCHEMBL13245216 | 0.96 | — | — | |
| SCHEMBL13245245 | 0.96 | — | — | |
| SCHEMBL13245141 | 0.96 | — | — | |
| SCHEMBL13244929 | 0.96 | — | — | |
| SCHEMBL13738316 | 0.93 | — | — | |
| SCHEMBL13245597 | 0.93 | — | — | |
| SCHEMBL13245099 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283175-A1 | ANTIBACTERIAL COMPOSITIONS | ACHAOGEN, INC. (US) | 2012-11-08 | — | — | US | claimed |
| WO-2011005355-A1 | COMBINATIONS COMPRISING A LPXC INHIBITOR AND AN ANTIBIOTIC FOR USE IN THE TREATMENT OF INFECTIONS CAUSED BY GRAM-NEGATIVE BACTERIA | ACHAOGEN, INC. (US) | 2011-01-13 | — | — | WO | claimed |
| US-9617256-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-20120283175-A1 | ANTIBACTERIAL COMPOSITIONS | ACHAOGEN, INC. (US) | 2012-11-08 | — | — | US | disclosed |
| WO-2011005355-A1 | COMBINATIONS COMPRISING A LPXC INHIBITOR AND AN ANTIBIOTIC FOR USE IN THE TREATMENT OF INFECTIONS CAUSED BY GRAM-NEGATIVE BACTERIA | ACHAOGEN, INC. (US) | 2011-01-13 | — | — | WO | disclosed |
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |