⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276387 | 1.00 | — | — | |
| SCHEMBL3107242 | 0.95 | — | — | |
| SCHEMBL27625504 | 0.95 | TRIM24 (0.82) | — | |
| Hydrochloric Acid SCHEMBL10943527 | 0.95 | — | — | |
| SCHEMBL1566729 | 0.95 | TRIM24 (0.82) | — | |
| SCHEMBL3111600 | 0.95 | — | — | |
| SCHEMBL3002760 | 0.95 | — | — | |
| SCHEMBL5822339 | 0.91 | TRIM24 (0.75) | — | |
| SCHEMBL5860219 | 0.91 | TRIM24 (0.91) | — | |
| SCHEMBL3700651 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5376685-A | Arylhydrazones using as SAMDC inhibitors | CIBA-GEIGY CORPORATION (US) | 1994-12-27 | — | — | US | disclosed |
| US-5238941-A | S-adenosylmethionine decarboxylase inhibitors | CIBA-GEIGY CORPORATION (US) | 1993-08-24 | — | — | US | disclosed |
| US-5118709-A | Decarboxylase enzyme inhibitors; antitumor agents | CIBA-GEIGY CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |
| US-4971986-A | ANTITUMOR AGENTS | CIBA-GEIGY CORPORATION (US) | 1990-11-20 | — | — | US | disclosed |