SCHEMBL932380

SCHEMBL932380

C[Si](C)(C)OCO[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18091112 0.84
SCHEMBL681951 0.83
SCHEMBL12716013 0.81
SCHEMBL12005162 0.78
SCHEMBL4610661 0.75
SCHEMBL10983138 0.73
SCHEMBL1223591 0.73
SCHEMBL14262194 0.71 HSD17B10 (0.33)
SCHEMBL27813 0.70
SCHEMBL13575280 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5670594-A POLYDIMETHYLSILOXANE POLYMERS WITH VINYL OR ACRYLATE GROUPS FOR INTRAOCULAR LENSES MENICON CO., LTD. (JP) 1997-09-23 US claimed
US-4826936-A Silicone-containing contact lens material and contact lenses made thereof POLYMER TECHNOLOGY CORP. (US) 1989-05-02 US claimed
US-4424328-A POLYMERS OF UNSATURATED MULTIFUNCTIONAL POLYSILOXANES POLYMER TECHNOLOGY CORPORATION (US) 1984-01-03 US claimed
US-20180000939-A1 NOVEL LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY SIRNA THERAPEUTICS, INC. (US) 2018-01-04 US disclosed
US-8536261-B2 Rubber composition containing treated silica and products with component thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2013-09-17 US disclosed
US-20130096260-A1 RUBBER COMPOSITION CONTAINING TREATED SILICA AND PRODUCTS WITH COMPONENT THEREOF GOODYEAR TIRE & RUBBER COMPANY, THE 2013-04-18 US disclosed
US-8349940-B2 Rubber composition containing treated silica and products with component thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2013-01-08 US disclosed
EP-2452212-A2 MONO ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUP CONTAINING POLYCARBOSILOXANE MONOMERS Bausch & Lomb Incorporated (US) 2012-05-16 EP disclosed
US-20110257331-A1 RUBBER COMPOSITION CONTAINING TREATED SILICA AND PRODUCTS WITH COMPONENT THEREOF GOODYEAR TIRE & RUBBER COMPANY, THE 2011-10-20 US disclosed
WO-2011005937-A2 MONO ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUP CONTAINING POLYCARBOSILOXANE MONOMERS BAUSCH & LOMB INCORPORATED (US) 2011-01-13 WO disclosed
US-20100316664-A1 Agent For Growing Fibroblasts SHISEIDO COMPANY, LTD. (JP) 2010-12-16 US disclosed
US-20100190879-A1 COMPOSITIONS COMPRISING FLUORINE-CONTAINING POLYMER AND SILOXANE HUNTSMAN TEXTILE EFFECTS (GERMANY) GMBH (US) 2010-07-29 US disclosed
EP-1930338-A1 Fumaric acid derivates and ophtalmic lenses using the same E-brain Corporation Ltd. (JP) 2008-06-11 EP disclosed
US-5399737-A Microbiocides ALCON LABORATORIES, INC. (US) 1995-03-21 US disclosed
US-4826936-A Silicone-containing contact lens material and contact lenses made thereof POLYMER TECHNOLOGY CORP. (US) 1989-05-02 US disclosed
US-4604479-A Silicone-containing contact lens material and contact lenses made thereof POLYMER TECHNOLOGY CORPORATION (US) 1986-08-05 US disclosed
US-4424328-A POLYMERS OF UNSATURATED MULTIFUNCTIONAL POLYSILOXANES POLYMER TECHNOLOGY CORPORATION (US) 1984-01-03 US disclosed