⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Norflurane SCHEMBL6376789 | 0.78 | — | — | |
| Norflurane SCHEMBL28923101 | 0.73 | — | — | |
| Norflurane SCHEMBL1173735 | 0.73 | — | — | |
| Norflurane SCHEMBL5466910 | 0.73 | — | — | |
| SCHEMBL1003267 | 0.73 | — | — | |
| Norflurane SCHEMBL11036325 | 0.73 | — | — | |
| Norflurane SCHEMBL9499 | 0.73 | — | — | |
| Norflurane SCHEMBL8973634 | 0.72 | TSHR (0.36) | — | |
| Norflurane SCHEMBL11849163 | 0.72 | — | — | |
| Norflurane SCHEMBL16162678 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110139848-B | Method for producing 1,2,2, 2-tetrafluoroethyl difluoromethyl ether (desflurane) | 中央硝子株式会社 | 2022-04-12 | — | — | CN | disclosed |
| EP-0583540-A1 | Synthesis of desflurane | Anaquest, Inc. (US) | 1994-02-23 | — | — | EP | disclosed |
| US-5205914-A | Synthesis of desflurane | ANAQUEST, INC. (US) | 1993-04-27 | — | — | US | disclosed |