Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.51 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9324908 | 0.90 | KMT2A (0.72) | KMT2AMEN1ATMPPARGPIN1 | |
| SCHEMBL9323487 | 0.88 | KMT2A (0.65) | KMT2AMEN1ATMPIN1PIN4 | |
| SCHEMBL9323639 | 0.88 | KMT2A (0.65) | KMT2AMEN1ATMPPARGPIN1 | |
| SCHEMBL9323818 | 0.87 | KMT2A (0.76) | KMT2AMEN1ATMPTPN1 | |
| SCHEMBL9323443 | 0.87 | KMT2A (0.68) | KMT2AMEN1ATMPIN1PIN4 | |
| SCHEMBL9322643 | 0.86 | KMT2A (0.78) | KMT2AMEN1ATMPTPN1 | |
| SCHEMBL8872124 | 0.85 | KMT2A (0.65) | KMT2AMEN1ATMPIN1PIN4 | |
| SCHEMBL8871842 | 0.84 | KMT2A (0.61) | KMT2AMEN1ATMPPARGPIN1 | |
| SCHEMBL9323606 | 0.83 | KMT2A (0.60) | KMT2AMEN1ATMPPARGPTPN1 | |
| SCHEMBL9325709 | 0.81 | KMT2A (0.67) | KMT2AMEN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353198-B1 | Parabanic acid derivatives and pharmaceutical compositions containing them | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1994-02-02 | — | — | EP | disclosed |
| US-4985453-A | DIABETES TREATMENT | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0353198-A1 | Parabanic acid derivatives and pharmaceutical compositions containing them | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1990-01-31 | — | — | EP | disclosed |