Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 10/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322468 | 0.85 | TACR1 (0.43) | TACR1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL9321956 | 0.85 | TACR1 (0.64) | TACR1 | |
| SCHEMBL9321907 | 0.85 | TACR1 (0.53) | TACR1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL9322762 | 0.84 | TACR1 (0.51) | TACR1CHRNB2CHRNA7CHRNA4 | |
| Hydrochloric Acid SCHEMBL9323145 | 0.83 | TACR1 (0.56) | TACR1 | |
| SCHEMBL9321890 | 0.83 | TACR1 (0.56) | TACR1 | |
| SCHEMBL9322963 | 0.82 | TACR1 (0.53) | TACR1CHRNB2CHRNA7CHRNA4BCHE | |
| SCHEMBL9322878 | 0.79 | TACR1 (0.73) | TACR1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL9324189 | 0.78 | TACR1 (0.53) | TACR1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL9322719 | 0.77 | TACR1 (0.53) | TACR1CHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409931-B1 | QUINUCLIDINE THERAPEUTIC AGENTS | PFIZER (US) | 1994-02-16 | — | — | EP | disclosed |
| WO-1990005525-A1 | QUINUCLIDINE DERIVATIVES AS SUBSTANCE P ANTAGONISTS | PFIZER INC. (US) | 1990-05-31 | — | — | WO | disclosed |