Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | GSR | P00390 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | NPY4R | P50391 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789422 | 1.00 | CHRM2 (0.47) | CHRM2CHRM1CHRM4CHRM3GSR | |
| SCHEMBL9325357 | 1.00 | CHRM2 (0.47) | CHRM2CHRM1CHRM4CHRM3GSR | |
| SCHEMBL2293227 | 0.95 | GSR (0.50) | CHRM2CHRM1CHRM4CHRM3GSR | |
| SCHEMBL2292809 | 0.95 | GSR (0.50) | CHRM2CHRM1CHRM4CHRM3GSR | |
| SCHEMBL2293222 | 0.95 | GSR (0.50) | CHRM2CHRM1CHRM4CHRM3GSR | |
| SCHEMBL4915341 | 0.93 | GSR (0.52) | CHRM2CHRM1CHRM4CHRM3GSR | |
| SCHEMBL16250349 | 0.93 | GSR (0.52) | CHRM2CHRM1CHRM4CHRM3GSR | |
| SCHEMBL14130633 | 0.87 | CHRM2 (0.44) | CHRM2CHRM1CHRM4CHRM3GSR | |
| SCHEMBL5084642 | 0.87 | CHRM2 (0.44) | CHRM2CHRM1CHRM4CHRM3GSR | |
| SCHEMBL20995891 | 0.85 | CHRM2 (0.53) | CHRM2CHRM1CHRM4CHRM3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053523-B | Azetidines as MEK inhibitors for the treatment of proliferative diseases | 埃克塞利希斯股份有限公司 | 2022-03-25 | — | — | CN | disclosed |
| US-5312950-A | Method for purification of alcohols | EASTMAN KODAK COMPANY (US) | 1994-05-17 | — | — | US | disclosed |