Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | YARS1 | P54577 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11431737 | 1.00 | MAPT (0.46) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL9567734 | 1.00 | MAPT (0.46) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL14288987 | 0.90 | MAPT (0.44) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL8597022 | 0.90 | ATM (0.42) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL7828421 | 0.90 | ATM (0.42) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL3731768 | 0.89 | MAPT (0.43) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL3731770 | 0.89 | MAPT (0.43) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL28435235 | 0.89 | MAPT (0.43) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL27461765 | 0.89 | MAPT (0.43) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL8113253 | 0.89 | MAPT (0.43) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103641847-A | Preparation method of cefoperazone acid | SHANDONG XINQUAN PHARMACEUTICAL CO LTD | 2014-03-19 | — | — | CN | disclosed |
| CN-102532168-A | Synthesis method of cefoperazone acid | SHANDONG XINQUAN MEDICINE CO LTD | 2012-07-04 | — | — | CN | disclosed |
| CN-1224619-C | HO-EPCP synthesizing method | SHANGHAI APPLIED TECHNOLOGY CO (CN) | 2005-10-26 | — | — | CN | disclosed |
| EP-0317484-B1 | N,N'-carboxyl-bis-(4-ethyl-2,3-dioxo)-piperazine, process for the preparation thereof and use thereof | GEMA SA (ES) | 1994-03-16 | — | — | EP | disclosed |
| EP-0550775-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1993-07-14 | — | — | EP | disclosed |
| EP-0492277-A2 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-07-01 | — | — | EP | disclosed |
| US-5015736-A | Piperazine intermediates | GEMA, S.A. (ES) | 1991-05-14 | — | — | US | disclosed |
| US-4985555-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4965358-A | N,N'-carbonyl-bis-(4-ethyl-2,3-dioxo)-piperazine | GEMA, S. A. (ES) | 1990-10-23 | — | — | US | disclosed |
| US-4877783-A | β-lactam antibacterial agents | BEECHAM GROUP P.L.C. (GB) | 1989-10-31 | — | — | US | disclosed |
| US-4327097-A | BACTERICIDES FOR MAMMALS | TOYAMA CHEMICAL CO., LTD. (JP) | 1982-04-27 | — | — | US | disclosed |
| EP-0048169-A2 | Bis-tetrazoylmethyl substituted cephalosporin antibiotics, their preparation and pharmaceutical formulations containing them | ELI LILLY AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |
| US-4304909-A | Process for producing 7-(D(-)-α-(4-ethyl-2,3-dioxo-1-piperazinecarboxamido)-α-(4-hydroxyphenyl)acetamido)-3-(5-(1-methyl-1,2,3,4-tetrazolyl)thiomethyl)-.DELTA.3 -cephem-4-carboxylic acid and a pharmaceutically acceptable salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 1981-12-08 | — | — | US | disclosed |
| US-4237280-A | Intermediate for cephalosporin type compound | TOYAMA CHEMICAL COMPANY, LIMITED (JP) | 1980-12-02 | — | — | US | disclosed |
| EP-0015240-A1 | Azacyclyl (thio) ureidoacetyl compounds and their preparation | CIBA-GEIGY AG (CH) | 1980-09-03 | — | — | EP | disclosed |
| US-4219554-A | Novel penicillins and cephalosporins and process for producing same | TOYAMA CHEMICAL COMPANY, LIMITED (JP) | 1980-08-26 | — | — | US | disclosed |
| US-4112090-A | BACTERICIDE | TOYAMA CHEMICAL CO., LTD. (JP) | 1978-09-05 | — | — | US | disclosed |
| US-4110327-A | BACTERICIDES | TOYAMA CHEMICAL CO., LTD. (JP) | 1978-08-29 | — | — | US | disclosed |
| US-4103008-A | ANTIBIOTICS | TOSHIYASU ISHIMARU | 1978-07-25 | — | — | US | disclosed |
| US-4087424-A | Novel penicillins and cephalosporins and process for producing the same | TOYAMA CHEMICAL CO., LTD. (JA) | 1978-05-02 | — | — | US | disclosed |