Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | CETP | P11597 | 1/20 | 0.53 |
| ▸ | IAPP | P10997 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8165390 | 1.00 | HPGD (0.59) | HPGDEPHX2KMT2AMEN1MAPT | |
| SCHEMBL30874195 | 1.00 | HPGD (0.59) | HPGDEPHX2KMT2AMEN1MAPT | |
| SCHEMBL4392253 | 1.00 | HPGD (0.59) | HPGDEPHX2KMT2AMEN1MAPT | |
| SCHEMBL5681564 | 1.00 | HPGD (0.59) | HPGDEPHX2KMT2AMEN1MAPT | |
| SCHEMBL12040749 | 0.98 | HPGD (0.61) | HPGDEPHX2KMT2AMEN1MAPT | |
| SCHEMBL27740469 | 0.93 | MAPT (0.59) | HPGDEPHX2KMT2AMEN1MAPT | |
| SCHEMBL10993722 | 0.93 | MAPT (0.65) | HPGDEPHX2KMT2AMEN1MAPT | |
| SCHEMBL10204017 | 0.93 | IAPP (0.60) | HPGDHDAC3ALDH1A1CES2CES1 | |
| SCHEMBL18800147 | 0.89 | MAPT (0.65) | EPHX2MAPTRXFP1HDAC3ALDH1A1 | |
| SCHEMBL28713178 | 0.86 | HPGD (0.59) | HPGDEPHX2HDAC3ALDH1A1IAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011003455-A1 | METHOD FOR PRODUCING 4-(ALKYL)-1-(2-METHYL-3-(2,6-DIMETHYLMORPHOLINE)PROPYL) BENZOL COMPOUNDS | CILAG AG (CH) | 2011-01-13 | — | — | WO | disclosed |