Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | PPARG | P37231 | 2/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.59 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | APEX1 | P27695 | 2/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9022062 | 0.94 | NR1I2 (0.51) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9021180 | 0.90 | NR1I2 (0.62) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9551564 | 0.89 | NR1I2 (0.62) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9551553 | 0.88 | NR1I2 (0.62) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9022572 | 0.86 | NR1I2 (0.59) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9020985 | 0.86 | NR1I2 (0.59) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| Iodide SCHEMBL9021079 | 0.86 | NR1I2 (0.59) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9329763 | 0.85 | NR1I2 (0.54) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9329069 | 0.85 | NR1I2 (0.57) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9326225 | 0.84 | NR1I2 (0.53) | NR1I2MAPTPPARGSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336768-A | Bactericides | HOFFMANN-LA ROCHE INC. (US) | 1994-08-09 | — | — | US | disclosed |