SCHEMBL9327883

SCHEMBL9327883

CC[C@H](C)CCCC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.48
GPR84 Q9NQS5 7/20 0.46
PPARG P37231 7/20 0.46
PPARD Q03181 7/20 0.46
PPARA Q07869 7/20 0.46
HDAC11 Q96DB2 5/20 0.46
TSHR P16473 4/20 0.46
PTPN1 P18031 3/20 0.46
ALDH1A1 P00352 2/20 0.46
TLR2 O60603 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
FABP4 P15090 2/20 0.46
SLC22A6 Q4U2R8 2/20 0.46
FFAR1 O14842 2/20 0.46
FFAR4 Q5NUL3 2/20 0.46
SLC22A8 Q8TCC7 1/20 0.46
MEN1 O00255 1/20 0.46
ESR1 P03372 1/20 0.46
ALOX15 P16050 1/20 0.46
PDE4A P27815 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL261797 1.00 AKR1B1 (0.48) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL10951489 0.96 FFAR4 (0.47) AKR1B1GPR84PPARGPPARDPPARA
Ethylene Glycol SCHEMBL5474843 0.94 CAMK2A (0.46) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL50063 0.93 FFAR4 (0.53) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL9499158 0.93 FFAR4 (0.53) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL6373776 0.93 FFAR4 (0.53) AKR1B1GPR84PPARGPPARDPPARA
Hydrochloric Acid SCHEMBL10695203 0.91 FFAR4 (0.52) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL22612553 0.91 FFAR4 (0.57) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL347119 0.91 FFAR4 (0.57) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL22612525 0.91 FFAR4 (0.57) AKR1B1GPR84PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
EP-3461835-A1 CYCLOSPORINE ANALOGUE MOLECULES MODIFIED AT AMINO ACID 1 AND 3 ContraVir Pharmaceuticals, Inc. (US) 2019-04-03 EP disclosed
WO-2012079172-A1 CYCLOSPORINE ANALOGUE MOLECULES MODIFIED AT AMINO ACID 1 AND 3 ISOTECHNIKA PHARMA INC. (CA) 2012-06-21 WO disclosed
EP-0306195-B1 Optically active-2,5-diphenylpyridines CHISSO CORP (JP) 1994-03-16 EP disclosed
EP-0260910-B1 3,6-DIPHENYLPYRIDAZINES Chisso Corporation (JP) 1992-05-27 EP disclosed
US-5047171-A Liquid Crystals CHISSO CORPORATION (JP) 1991-09-10 US disclosed
US-4818430-A LIQUID CRYSTALS CHISSO CORPORATION (JP) 1989-04-04 US disclosed
EP-0306195-A2 Optically active-2,5-diphenylpyridines Chisso Corporation (JP) 1989-03-08 EP disclosed
EP-0260910-A1 3,6-Diphenylpyridazines Chisso Corporation (JP) 1988-03-23 EP disclosed