Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | POLG | P54098 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.46 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6038227 | 0.91 | POLG (0.57) | POLBPOLGLMNACACNA1FALB | |
| SCHEMBL5038295 | 0.90 | POLB (0.62) | POLBPOLGLMNACACNA1FALB | |
| SCHEMBL4303303 | 0.90 | POLB (0.57) | POLBPOLGLMNACACNA1FALB | |
| SCHEMBL16312542 | 0.90 | POLB (0.62) | POLBPOLGLMNACACNA1FALB | |
| SCHEMBL10228314 | 0.89 | POLB (0.56) | POLBPOLGLMNACACNA1FALB | |
| SCHEMBL10331118 | 0.89 | POLB (0.56) | POLBPOLGLMNACACNA1FALB | |
| SCHEMBL6522346 | 0.89 | POLB (0.56) | POLBPOLGLMNACACNA1FALB | |
| SCHEMBL17027928 | 0.89 | POLB (0.56) | POLBPOLGLMNACACNA1FALB | |
| SCHEMBL1970390 | 0.88 | POLB (0.57) | POLBPOLGLMNACACNA1FALB | |
| SCHEMBL1970398 | 0.88 | POLB (0.57) | POLBPOLGLMNACACNA1FALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3049814-A1 | METHOD | Isis Innovation Limited (GB) | 2016-08-03 | — | — | EP | disclosed |
| WO-2015040423-A1 | METHOD | ISIS INNOVATION LIMITED (GB) | 2015-03-26 | — | — | WO | disclosed |
| EP-0133473-B1 | In vivo labelling of polynucleotide sequences | ENZO BIOCHEM INC (US) | 1994-03-23 | — | — | EP | disclosed |
| US-4987065-A | GENETIC ENGINEERING | ENZO BIOCHEM, INC. (US) | 1991-01-22 | — | — | US | disclosed |
| EP-0133473-A2 | In vivo labelling of polynucleotide sequences | ENZO BIOCHEM, INC. (US) | 1985-02-27 | — | — | EP | disclosed |