Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.53 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711386 | 0.86 | CYP19A1 (0.55) | CYP19A1CYP26A1KMT2AMEN1CYP1A2 | |
| SCHEMBL10924520 | 0.85 | CYP19A1 (0.49) | CYP19A1CYP26A1KMT2AMEN1CYP1A2 | |
| SCHEMBL27494651 | 0.80 | CYP19A1 (0.57) | CYP19A1CYP26A1KMT2AMEN1CYP1A2 | |
| SCHEMBL11320884 | 0.79 | CYP19A1 (0.49) | CYP19A1CYP26A1KMT2AMEN1CYP1A2 | |
| SCHEMBL10408460 | 0.79 | CYP19A1 (0.56) | CYP19A1CYP26A1KMT2AMEN1CYP1A2 | |
| SCHEMBL14857936 | 0.78 | KMT2A (0.51) | CYP26A1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11335075 | 0.77 | CYP19A1 (0.50) | CYP19A1CYP26A1KMT2AMEN1CYP1A2 | |
| SCHEMBL11106057 | 0.76 | KMT2A (0.48) | CYP19A1CYP26A1KMT2AMEN1CYP1A2 | |
| SCHEMBL11321101 | 0.75 | CYP19A1 (0.48) | CYP19A1CYP26A1KMT2AMEN1CYP1A2 | |
| SCHEMBL15565117 | 0.74 | KMT2A (0.48) | KMT2AMEN1ALDH1A1LMNAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424021-B1 | Antimuscarinic bronchodilators | PFIZER LTD (GB) | 1994-03-02 | — | — | EP | disclosed |
| US-5171744-A | Antimuscarinic bronchodilators | PFIZER INC. (US) | 1992-12-15 | — | — | US | disclosed |
| EP-0424021-A1 | Antimuscarinic bronchodilators | Pfizer Limited (GB) | 1991-04-24 | — | — | EP | disclosed |