SCHEMBL9328267

SCHEMBL9328267

CCCCCCCCOP(=O)(OBr)OBr

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.60
LPAR3 Q9UBY5 8/20 0.57
LPAR2 Q9HBW0 6/20 0.57
LPAR1 Q92633 3/20 0.57
TSHR P16473 1/20 0.47
CDC25A P30304 2/20 0.46
LMNA P02545 1/20 0.46
ESR1 P03372 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
AGTR1 P30556 1/20 0.46
AKT1 P31749 1/20 0.46
ADRA1A P35348 1/20 0.46
KCNH2 Q12809 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25174022 1.00 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL25176409 0.98 CYP3A4 (0.62) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL11585764 0.91 CYP3A4 (0.73) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL25173881 0.88 CYP3A4 (0.52) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL25174087 0.88 CYP3A4 (0.52) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL25173752 0.88 CYP3A4 (0.52) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL25167788 0.88 CYP3A4 (0.52) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL21439847 0.86 CYP3A4 (0.80) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL22230793 0.86 CYP3A4 (0.80) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL20483847 0.86 CYP3A4 (0.80) CYP3A4LPAR3LPAR2LPAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0358985-B1 Method of transhalogenating a halophosphorus compound with fluoride ETHYL CORP (US) 1994-03-16 EP disclosed
EP-0312790-B1 Process for transhalogenating a halophosphorus compound with fluoride ETHYL CORP (US) 1993-11-18 EP disclosed
US-5136075-A Process for transhalogenating a halophosphorus compound with fluoride ETHYL CORPORATION (US) 1992-08-04 US disclosed
US-5061818-A Fluorination with metal or ammonium fluoride in presence of pyridine halide salt ETHYL CORPORATION (US) 1991-10-29 US disclosed
US-5049691-A Process for transhalogenating a halophosphorous compound with anhydrous hydrogen fluoride ETHYL CORPORATION (US) 1991-09-17 US disclosed
US-4929745-A Transhalogenation of halophosphorus compounds EHTYL CORPORATION (US) 1990-05-29 US disclosed
EP-0358985-A1 Method of transhalogenating a halophosphorus compound with fluoride ETHYL CORPORATION (US) 1990-03-21 EP disclosed
US-4910324-A Using a metal or ammonium fluoride ETHYL CORPORATION (US) 1990-03-20 US disclosed
EP-0357048-A2 Process for transhalogenating a halophosphorus compound with hydrogen fluoride ALBEMARLE CORPORATION (US) 1990-03-07 EP disclosed
EP-0353598-A2 Transhalogenation of halophosphorus compounds ETHYL CORPORATION (US) 1990-02-07 EP disclosed
EP-0312790-A2 Process for transhalogenating a halophosphorus compound with fluoride ETHYL CORPORATION (US) 1989-04-26 EP disclosed