Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | RARA | P10276 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329247 | 1.00 | RARB (0.65) | RARBTP53TSHRPTPN11PLA2G4B | |
| SCHEMBL9330512 | 1.00 | RARB (0.65) | RARBTP53TSHRPTPN11PLA2G4B | |
| SCHEMBL9331239 | 1.00 | RARB (0.65) | RARBTP53TSHRPTPN11PLA2G4B | |
| SCHEMBL8162563 | 0.96 | TP53 (0.62) | RARBTP53TSHRPTPN11PLA2G4B | |
| SCHEMBL9329676 | 0.96 | TP53 (0.62) | RARBTP53TSHRPTPN11PLA2G4B | |
| SCHEMBL9329632 | 0.96 | TP53 (0.62) | RARBTP53TSHRPTPN11PLA2G4B | |
| SCHEMBL9761929 | 0.90 | RARB (0.72) | RARBTP53TSHRPTPN11PLA2G4B | |
| SCHEMBL9761346 | 0.90 | RARB (0.72) | RARBTP53TSHRPTPN11PLA2G4B | |
| SCHEMBL9328518 | 0.90 | RARB (0.50) | RARBPTPN11MEN1ALDH1A1RARA | |
| SCHEMBL9257016 | 0.90 | TP53 (0.57) | RARBTP53TSHRPLA2G4BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332675-A | Liquid crystals | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0289307-B1 | OPTICALLY ACTIVE AROMATIC CARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-5019298-A | Optically active aromatic carboxylic acid derivatives and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-05-28 | — | — | US | disclosed |
| EP-0289307-A2 | Optically active aromatic carboxylic acid derivatives and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-11-02 | — | — | EP | disclosed |