Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331673 | 0.95 | HIF1A (0.62) | HIF1AKDM4EHDAC3HDAC1HDAC6 | |
| SCHEMBL9329351 | 0.90 | HIF1A (0.67) | HIF1AKDM4EHDAC3HDAC1HDAC6 | |
| SCHEMBL11922674 | 0.83 | HIF1A (0.66) | HIF1AKDM4EHDAC3HDAC1HDAC6 | |
| SCHEMBL2891414 | 0.82 | HDAC3 (0.69) | HIF1AKDM4EHDAC3HDAC1HDAC6 | |
| SCHEMBL9331152 | 0.82 | HIF1A (0.58) | HIF1AKDM4EHDAC3HDAC1HDAC6 | |
| SCHEMBL2642829 | 0.81 | HIF1A (0.60) | HIF1AKDM4EHDAC3HDAC1HDAC6 | |
| SCHEMBL16523499 | 0.81 | HIF1A (0.60) | HIF1AKDM4EHDAC3HDAC1HDAC6 | |
| SCHEMBL26374347 | 0.81 | HDAC3 (0.49) | HIF1AHDAC3HDAC1HDAC6ALDH1A1 | |
| SCHEMBL15296755 | 0.80 | HIF1A (0.59) | HIF1AKDM4EHDAC3HDAC1HDAC6 | |
| SCHEMBL14206509 | 0.79 | HDAC3 (0.45) | HIF1AKDM4EHDAC3HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300400-B1 | Nitric acid ester derivative | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-03-16 | — | — | EP | disclosed |
| CN-1021046-C | PREPARING METHOD FOR NITRIC ESTER DERIVATIVE | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-06-02 | — | — | CN | disclosed |
| US-4923886-A | VASODILATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-08 | — | — | US | disclosed |
| CN-1031226-A | Nitrate derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1989-02-22 | — | — | CN | disclosed |
| EP-0300400-A1 | Nitric acid ester derivative | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-01-25 | — | — | EP | disclosed |