⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28784562 | 0.97 | — | — | |
| SCHEMBL7889087 | 0.74 | — | — | |
| SCHEMBL1116313 | 0.67 | — | — | |
| SCHEMBL10545322 | 0.65 | — | — | |
| SCHEMBL4448355 | 0.64 | — | — | |
| SCHEMBL422813 | 0.63 | — | — | |
| SCHEMBL3594632 | 0.62 | — | — | |
| SCHEMBL2105444 | 0.62 | TDP1 (0.30) | — | |
| SCHEMBL30124666 | 0.62 | — | — | |
| SCHEMBL9521550 | 0.62 | MEN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990001929-A1 | NEW MEDICAL USE | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-03-08 | — | — | WO | claimed |
| EP-0196184-A2 | Aryl derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-10-01 | — | — | EP | claimed |
| CN-111943890-B | Pharmaceutical compounds | 艾欧米制药有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-111943890-A | Pharmaceutical compounds | 艾欧米制药有限公司 | 2020-11-17 | — | — | CN | disclosed |
| CN-107108556-B | Pharmaceutical compounds | 艾欧米制药有限公司 | 2020-09-29 | — | — | CN | disclosed |
| CN-101805293-B | 1 (dimethylamino) ethyl, 3-hydroxy-imidazoline hydrochloride and preparation method thereof | SHIBAO NIE | 2011-08-24 | — | — | CN | disclosed |
| CN-101805293-A | 1 (dimethylamino) ethyl, 3-hydroxy-imidazoline hydrochloride and preparation method thereof | SHIBAO NIE | 2010-08-18 | — | — | CN | disclosed |
| CN-1202800-A | Herbicidal composition | NOVARTIS AG (CH) | 1998-12-23 | — | — | CN | disclosed |
| CN-1144526-A | Thiazolidines and oxazolidines substituted by pyridine ring and their use a hypoglycemic agents | NISSAN CHEMICAL IND LTD (JP) | 1997-03-05 | — | — | CN | disclosed |
| US-5292884-A | Cyclic hydroxamic acids | BIOMIDE INVESTMENT LIMITED PARTNERSHIP (US) | 1994-03-08 | — | — | US | disclosed |
| US-5234933-A | Antiflammatory agents, enzyme inhibitors | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY AND VANDERBILT UNIVERSITY (US) | 1993-08-10 | — | — | US | disclosed |
| US-5036157-A | Hydroxamic acid derivatives, lipoxygenase and cyclooxygenase inhibitors, anticoagulants, antiinflammatory agents | BURROUGHS WELLCOME CO. | 1991-07-30 | — | — | US | disclosed |
| US-4988733-A | Also used in treatment of cardiovascular disorders and inflammation | BURROUGHS WELLCOME CO. (US) | 1991-01-29 | — | — | US | disclosed |
| US-4977188-A | Hydroamic acid derivatives | BURROUGHS WELLCOME CO. (US) | 1990-12-11 | — | — | US | disclosed |
| WO-1990001929-A1 | NEW MEDICAL USE | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-03-08 | — | — | WO | disclosed |
| EP-0299761-A1 | Anti-inflammatory aryl derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1989-01-18 | — | — | EP | disclosed |
| US-4738986-A | CYCLOOXYGENASE, LIDOXYGENASE INHIBITORS | BURROUGHS WELLCOME CO. (US) | 1988-04-19 | — | — | US | disclosed |
| US-4738986-A | CYCLOOXYGENASE, LIDOXYGENASE INHIBITORS | BURROUGHS WELLCOME CO. (US) | 1988-04-19 | — | — | US | disclosed |
| EP-0196184-A2 | Aryl derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-10-01 | — | — | EP | disclosed |
| EP-0196184-A2 | Aryl derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-10-01 | — | — | EP | disclosed |