Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 6/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330227 | 1.00 | HSD17B10 (0.36) | HSD17B10CTSDBACE1MAPKAPK2ADAMTS5 | |
| SCHEMBL11368398 | 0.82 | HSD17B10 (0.32) | HSD17B10CYP3A4CYP2D6MAPTHRH2 | |
| SCHEMBL11366186 | 0.82 | BCHE (0.40) | HSD17B10CYP3A4CYP2D6MAPTHRH2 | |
| SCHEMBL11366182 | 0.82 | BCHE (0.40) | HSD17B10CYP3A4CYP2D6MAPTHRH2 | |
| SCHEMBL11368315 | 0.82 | HSD17B10 (0.32) | HSD17B10CYP3A4CYP2D6MAPTHRH2 | |
| SCHEMBL11368335 | 0.76 | HSD17B10 (0.35) | HSD17B10HRH4 | |
| SCHEMBL9328933 | 0.75 | CYP3A4 (0.42) | HSD17B10CYP3A4CYP2D6MAPTHRH2 | |
| SCHEMBL11368363 | 0.70 | CYP3A4 (0.43) | HSD17B10CYP3A4CYP2D6MAPTHRH2 | |
| SCHEMBL11485667 | 0.69 | BCHE (0.41) | CYP3A4CYP2D6MAPTHRH2HRH4 | |
| SCHEMBL11485664 | 0.69 | BCHE (0.41) | CYP3A4CYP2D6MAPTHRH2HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364844-B1 | Insecticidally active cyano compounds | BAYER AGROCHEM KK (JP) | 1994-03-16 | — | — | EP | claimed |
| EP-0364844-B1 | Insecticidally active cyano compounds | BAYER AGROCHEM KK (JP) | 1994-03-16 | — | — | EP | disclosed |