Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9328954 | 1.00 | HSD17B2 (0.40) | HSD17B2EPHX2CCR5SIGMAR1MEN1 | |
| SCHEMBL9329407 | 1.00 | HSD17B2 (0.40) | HSD17B2EPHX2CCR5SIGMAR1MEN1 | |
| SCHEMBL9328959 | 1.00 | HSD17B2 (0.40) | HSD17B2EPHX2CCR5SIGMAR1MEN1 | |
| SCHEMBL9329416 | 1.00 | HSD17B2 (0.40) | HSD17B2EPHX2CCR5SIGMAR1MEN1 | |
| SCHEMBL9331285 | 0.84 | MFN2 (0.41) | — | |
| SCHEMBL9329348 | 0.83 | MEN1 (0.44) | MEN1TP53CYP1A2KMT2A | |
| SCHEMBL9330020 | 0.83 | MEN1 (0.44) | MEN1TP53CYP1A2KMT2A | |
| SCHEMBL9542082 | 0.83 | MEN1 (0.44) | MEN1TP53CYP1A2KMT2A | |
| SCHEMBL9330025 | 0.83 | MEN1 (0.44) | MEN1TP53CYP1A2KMT2A | |
| SCHEMBL9329339 | 0.83 | MEN1 (0.44) | MEN1TP53CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292884-A | Cyclic hydroxamic acids | BIOMIDE INVESTMENT LIMITED PARTNERSHIP (US) | 1994-03-08 | — | — | US | disclosed |