Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.43 |
| ▸ | RARB | P10826 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329632 | 0.80 | TP53 (0.62) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL8162563 | 0.80 | TP53 (0.62) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL9329676 | 0.80 | TP53 (0.62) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL9547780 | 0.80 | NR5A1 (0.36) | TP53MAPTALDH1A1 | |
| SCHEMBL9547777 | 0.80 | NR5A1 (0.36) | TP53MAPTALDH1A1 | |
| SCHEMBL9547784 | 0.80 | NR5A1 (0.36) | TP53MAPTALDH1A1 | |
| SCHEMBL9257016 | 0.80 | TP53 (0.57) | TP53TSHRPLA2G4BRARBKMT2A | |
| SCHEMBL9574389 | 0.80 | PLA2G4B (0.63) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL9417076 | 0.78 | PLA2G4B (0.65) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL9574428 | 0.78 | PLA2G4B (0.65) | TP53TSHRPLA2G4BRARBPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332675-A | Liquid crystals | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0289307-B1 | OPTICALLY ACTIVE AROMATIC CARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-5019298-A | Optically active aromatic carboxylic acid derivatives and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-05-28 | — | — | US | disclosed |
| EP-0289307-A2 | Optically active aromatic carboxylic acid derivatives and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-11-02 | — | — | EP | disclosed |