SCHEMBL9329147

SCHEMBL9329147

CC(O)c1ccc(C(=O)OCc2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.67
TDP1 Q9NUW8 4/20 0.67
SLC6A2 P23975 1/20 0.67
SLC6A3 Q01959 1/20 0.67
LMNA P02545 3/20 0.66
ALDH1A1 P00352 7/20 0.61
MAPT P10636 5/20 0.61
HPGD P15428 1/20 0.61
RAB9A P51151 3/20 0.59
GAA P10253 1/20 0.59
SMN1; SMN2 Q16637 2/20 0.54
NPC1 O15118 1/20 0.54
MEN1 O00255 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.50
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49
CYP3A4 P08684 2/20 0.47
ADRB2 P07550 1/20 0.47
ADRB1 P08588 1/20 0.47
ADRB3 P13945 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9329526 0.96 KMT2A (0.61) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL15614364 0.89 KMT2A (0.69) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL19822825 0.88 MAPT (0.60) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL12031732 0.87 TDP1 (0.71) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL27564674 0.87 KMT2A (0.61) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL22643562 0.86 KMT2A (0.65) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL27542643 0.86 TDP1 (0.65) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL23795853 0.85 KMT2A (0.63) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL13144171 0.85 KMT2A (0.63) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL312287 0.85 KMT2A (0.92) KMT2ATDP1SLC6A2SLC6A3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5332675-A Liquid crystals SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-07-26 US disclosed
EP-0289307-B1 OPTICALLY ACTIVE AROMATIC CARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-07-08 EP disclosed
US-5019298-A Optically active aromatic carboxylic acid derivatives and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-05-28 US disclosed
EP-0289307-A2 Optically active aromatic carboxylic acid derivatives and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-11-02 EP disclosed