Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 3/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9328905 | 1.00 | CFTR (0.46) | CFTRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9329435 | 1.00 | CFTR (0.46) | CFTRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9453539 | 1.00 | CFTR (0.46) | CFTRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9453557 | 1.00 | CFTR (0.46) | CFTRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9453554 | 1.00 | CFTR (0.46) | CFTRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9329460 | 1.00 | CFTR (0.46) | CFTRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9328914 | 1.00 | CFTR (0.46) | CFTRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9453537 | 1.00 | CFTR (0.46) | CFTRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9331268 | 1.00 | CFTR (0.46) | CFTRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9331934 | 1.00 | CFTR (0.46) | CFTRALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292884-A | Cyclic hydroxamic acids | BIOMIDE INVESTMENT LIMITED PARTNERSHIP (US) | 1994-03-08 | — | — | US | disclosed |
| US-5234933-A | Antiflammatory agents, enzyme inhibitors | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY AND VANDERBILT UNIVERSITY (US) | 1993-08-10 | — | — | US | disclosed |
| WO-1993008803-A1 | CYCLIC HYDROXAMIC ACIDS | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1993-05-13 | — | — | WO | disclosed |