Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.57 |
| ▸ | RARA | P10276 | 2/20 | 0.57 |
| ▸ | RARG | P13631 | 1/20 | 0.57 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16258012 | 0.98 | RARB (0.59) | RARBRARARARGCYP17A1CYP11B1 | |
| SCHEMBL3611490 | 0.98 | RARB (0.59) | RARBRARARARGCYP17A1CYP11B1 | |
| SCHEMBL16258119 | 0.98 | RARB (0.59) | RARBRARARARGCYP17A1CYP11B1 | |
| SCHEMBL8375678 | 0.95 | RARB (0.64) | RARBRARARARGCYP17A1CYP11B1 | |
| SCHEMBL10379732 | 0.94 | RARB (0.59) | RARBRARARARGCYP17A1CYP11B1 | |
| SCHEMBL16258015 | 0.93 | RARB (0.66) | RARBRARARARGCYP17A1CYP11B1 | |
| SCHEMBL16258029 | 0.93 | RARB (0.66) | RARBRARARARGCYP17A1CYP11B1 | |
| SCHEMBL16258039 | 0.93 | RARB (0.66) | RARBRARARARGCYP17A1CYP11B1 | |
| SCHEMBL11035363 | 0.91 | RARB (0.68) | RARBRARARARGCYP17A1CYP11B1 | |
| SCHEMBL16258040 | 0.90 | RARB (0.52) | RARBRARARARGCYP17A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429558-B1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK PATENT GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |