Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Anthraquinone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.86 |
| ▸ | CDC25B | P30305 | 3/20 | 0.86 |
| ▸ | MAOA | P21397 | 5/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | APAF1 | O14727 | 2/20 | 0.69 |
| ▸ | TDP2 | O95551 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | S100A4 | P26447 | 2/20 | 0.69 |
| ▸ | BLM | P54132 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | CES2 | O00748 | 1/20 | 0.69 |
| ▸ | TERT | O14746 | 1/20 | 0.69 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.69 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anthraquinone SCHEMBL28230151 | 0.96 | MEN1 (0.92) | MEN1KMT2ACDC25BMAOARAB9A | |
| Anthraquinone SCHEMBL28300718 | 0.96 | MEN1 (0.92) | MEN1KMT2ACDC25BMAOARAB9A | |
| Anthraquinone SCHEMBL9178171 | 0.96 | MEN1 (0.92) | MEN1KMT2ACDC25BMAOARAB9A | |
| Anthraquinone SCHEMBL28259565 | 0.96 | MEN1 (0.92) | MEN1KMT2ACDC25BMAOARAB9A | |
| Anthraquinone SCHEMBL28192712 | 0.93 | MEN1 (0.86) | MEN1KMT2ACDC25BMAOARAB9A | |
| SCHEMBL27265436 | 0.93 | MEN1 (0.86) | MEN1KMT2ACDC25BMAOARAB9A | |
| Anthraquinone SCHEMBL14943 | 0.93 | MEN1 (1.00) | MEN1KMT2ACDC25BMAOARAB9A | |
| Anthraquinone SCHEMBL1901249 | 0.93 | MEN1 (1.00) | MEN1KMT2ACDC25BMAOARAB9A | |
| Anthraquinone SCHEMBL29358690 | 0.93 | MEN1 (1.00) | MEN1KMT2ACDC25BMAOARAB9A | |
| SCHEMBL20203661 | 0.89 | MEN1 (0.92) | MEN1KMT2ACDC25BMAOARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117014-A | Bromination | EASTMAN KODAK COMPANY (US) | 1992-05-26 | — | — | US | claimed |
| EP-0585395-A1 | PROCESS FOR THE PREPARATION OF 1-AMINO-4-BROMOANTHRAQUINONES | EASTMAN CHEMICAL COMPANY (US) | 1994-03-09 | — | — | EP | disclosed |
| WO-1992019586-A1 | PROCESS FOR THE PREPARATION OF 1-AMINO-4-BROMOANTHRAQUINONES | EASTMAN KODAK COMPANY (US) | 1992-11-12 | — | — | WO | disclosed |