Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 7/20 | 0.52 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | BMP1 | P13497 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1509781 | 0.93 | AVPR1B (0.54) | AVPR1BAVPR1APLGBMP1F2 | |
| SCHEMBL7898282 | 0.93 | AVPR1B (0.54) | AVPR1BAVPR1APLGBMP1F2 | |
| SCHEMBL1509780 | 0.93 | AVPR1B (0.54) | AVPR1BAVPR1APLGBMP1F2 | |
| SCHEMBL30007346 | 0.93 | AVPR1B (0.54) | AVPR1BAVPR1APLGBMP1F2 | |
| SCHEMBL29816989 | 0.89 | AVPR1B (0.48) | AVPR1BAVPR1APLGBMP1F2 | |
| SCHEMBL2873083 | 0.89 | AVPR1B (0.48) | AVPR1BAVPR1APLGBMP1F2 | |
| SCHEMBL1738663 | 0.89 | AVPR1B (0.52) | AVPR1BAVPR1APLGBMP1 | |
| SCHEMBL3501647 | 0.88 | AVPR1B (0.47) | AVPR1BAVPR1APLGBMP1F2 | |
| SCHEMBL7368157 | 0.88 | AVPR1B (0.47) | AVPR1BAVPR1APLGBMP1F2 | |
| SCHEMBL7171393 | 0.83 | AVPR1B (0.46) | AVPR1BAVPR1APLGBMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375058-B1 | New retro-inverso analogues of trymopentin, the method for their synthesis and their use in the preparation of pharmaceutical compositions | SCLAVO SPA (IT) | 1994-03-16 | — | — | EP | disclosed |
| EP-0375040-B1 | Process for the preparation of retro-inverso peptides and new intermediates thereof | SCLAVO SPA (IT) | 1994-03-16 | — | — | EP | disclosed |
| EP-0375058-A2 | New retro-inverso analogues of trymopentin, the method for their synthesis and their use in the preparation of pharmaceutical compositions | SCLAVO S.p.A. (IT) | 1990-06-27 | — | — | EP | disclosed |