Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329706 | 0.82 | MAPK1 (0.52) | MAPK1ALDH1A1HPGDPOLBHTT | |
| SCHEMBL9331863 | 0.80 | MAPK1 (0.50) | MAPK1ALDH1A1HPGDPOLBHTT | |
| SCHEMBL9329762 | 0.78 | MAPK1 (0.51) | MAPK1ALDH1A1HPGDPOLBHTT | |
| SCHEMBL9329720 | 0.78 | MAPK1 (0.48) | MAPK1ALDH1A1HPGDPOLBHTT | |
| SCHEMBL9331921 | 0.78 | MAPK1 (0.56) | MAPK1ALDH1A1HPGDPOLBHTT | |
| SCHEMBL9331927 | 0.78 | MAPK1 (0.56) | MAPK1ALDH1A1HPGDPOLBHTT | |
| SCHEMBL9329655 | 0.76 | MAPK1 (0.46) | MAPK1ALDH1A1HPGDPOLBHTT | |
| SCHEMBL9331944 | 0.75 | MAPK1 (0.48) | MAPK1ALDH1A1HPGDPOLBHTT | |
| SCHEMBL9329318 | 0.74 | MAPK1 (0.47) | MAPK1ALDH1A1HPGDPOLBHTT | |
| SCHEMBL9329756 | 0.73 | MEN1 (0.49) | MAPK1ALDH1A1HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393109-B1 | NOVEL 2,3-THIOMORPHOLINEDIONE-2-OXIME DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | RICHTER GEDEON VEGYESZET (HU) | 1994-03-23 | — | — | EP | disclosed |
| US-5106846-A | Antiulcer agents | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1992-04-21 | — | — | US | disclosed |