Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ITGA4 | P13612 | 9/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CAD | P27708 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Limazocic SCHEMBL1230921 | 1.00 | HTT (0.58) | HTTITGA4KMT2ACADITGB1 | |
| Limazocic SCHEMBL9326335 | 1.00 | HTT (0.58) | HTTITGA4KMT2ACADITGB1 | |
| SCHEMBL22860783 | 0.85 | HTT (0.41) | HTTITGA4KMT2A | |
| SCHEMBL22860767 | 0.85 | HTT (0.41) | HTTITGA4KMT2A | |
| SCHEMBL22860770 | 0.83 | HTT (0.40) | HTTITGA4KMT2A | |
| SCHEMBL22860806 | 0.83 | KMT2A (0.61) | HTTITGA4KMT2A | |
| SCHEMBL9326232 | 0.83 | KMT2A (0.61) | HTTITGA4KMT2A | |
| SCHEMBL22860795 | 0.83 | HTT (0.40) | HTTITGA4KMT2A | |
| SCHEMBL22860762 | 0.80 | HTT (0.38) | HTTITGA4KMT2AITGB1 | |
| SCHEMBL9329782 | 0.80 | HTT (0.50) | HTTITGA4KMT2ACADITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356006-B1 | Cyclic sulfur-containing compounds | SANTEN PHARMACEUTICAL CO LTD (JP) | 1994-03-02 | — | — | EP | disclosed |
| US-5128467-A | Immunomodulation, liver disorders | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| US-5082836-A | Autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |
| US-5041435-A | Treatment of Liver Disorders and Autoimmune Diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0356006-A1 | Cyclic sulfur-containing compounds | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |