Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329498 | 0.84 | PDE3B (0.50) | PDE3BPDE3AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL15566518 | 0.76 | DAO (0.52) | PDE3BPDE3AKDM4EDAOGRIN2D | |
| SCHEMBL12561491 | 0.76 | DAO (0.43) | PDE3BPDE3AKDM4EDAOGRIN2D | |
| SCHEMBL9330011 | 0.76 | PDE3B (0.54) | PDE3BPDE3AHSD17B10KDM4EMAPT | |
| Medorinone SCHEMBL121782 | 0.71 | PDE3B (1.00) | PDE3BPDE3AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL14494387 | 0.71 | PDE3B (0.53) | PDE3BPDE3AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL9332815 | 0.71 | DAO (0.39) | PDE3BPDE3AKDM4EDAOGRIN2D | |
| SCHEMBL10809624 | 0.69 | PDE3B (0.60) | PDE3BPDE3AKDM4EALDH1A1TSHR | |
| SCHEMBL10812608 | 0.69 | PDE3B (0.60) | PDE3BPDE3AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL19153189 | 0.69 | PDE3B (0.40) | PDE3BPDE3AHSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589914-A1 | NOVEL 3-FUSED PYRIDINIUMMETHYL CEPHALOSPORINS | CHEIL FOODS & CHEMICALS, INC. (KR) | 1994-04-06 | — | — | EP | disclosed |