⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL27347124 | 0.89 | — | — | |
| SCHEMBL5666576 | 0.84 | — | — | |
| SCHEMBL20184137 | 0.79 | — | — | |
| SCHEMBL25433863 | 0.77 | — | — | |
| SCHEMBL25432325 | 0.70 | — | — | |
| SCHEMBL25432840 | 0.69 | — | — | |
| SCHEMBL25433976 | 0.65 | — | — | |
| SCHEMBL7081895 | 0.65 | — | — | |
| SCHEMBL20162411 | 0.65 | — | — | |
| SCHEMBL4022349 | 0.64 | SLC6A2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4704832-A2 | BIFUNCTIONAL SMALL MOLECULES TO TARGET THE SELECTIVE DEGRADATION OF CIRCULATING PROTEINS | Biohaven Therapeutics Ltd. (VG) | 2026-03-11 | — | — | EP | claimed |
| US-12485178-B2 | Bifunctional small molecules to target the selective degradation of circulating proteins | YALE UNIVERSITY (US) | 2025-12-02 | — | — | US | claimed |
| US-20250269043-A1 | TARGETED BIFUNCTIONAL DEGRADERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2025-08-28 | — | — | US | claimed |
| WO-2024227119-A2 | BIFUNCTIONAL SMALL MOLECULES TO TARGET THE SELECTIVE DEGRADATION OF CIRCULATING PROTEINS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-10-31 | — | — | WO | claimed |
| US-20240342293-A1 | ENGINEERED ANTIBODIES AS MOLECULAR DEGRADERS THROUGH CELLULAR RECEPTORS | YALE UNIVERSITY | 2024-10-17 | — | — | US | claimed |
| US-12083181-B2 | Bi-functional molecules to degrade circulating proteins | YALE UNIVERSITY (US) | 2024-09-10 | — | — | US | claimed |
| WO-2024167900-A2 | BIFUNCTIONAL MOLECULES TO TARGET DEGRADATION OF TUMOR NECROSIS FACTOR | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-08-15 | — | — | WO | claimed |
| WO-2024167879-A1 | BIFUNCTIONAL MOLECULES TO TARGET DEGRADATION OF INTERLEUKIN 17A (IL-17A) | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-08-15 | — | — | WO | claimed |
| US-20240181067-A1 | TARGETED BIFUNCTIONAL DEGRADERS AND METHODS USING SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-06-06 | — | — | US | claimed |
| US-20240148885-A1 | TARGETED BIFUNCTIONAL DEGRADERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-05-09 | — | — | US | claimed |
| EP-3773729-A1 | BI-FUNCTIONAL MOLECULES TO DEGRADE CIRCULATING PROTEINS | Yale University (US) | 2021-02-17 | — | — | EP | claimed |
| CN-112236169-A | Bifunctional small molecules targeting selective degradation of circulating proteins | 耶鲁大学 | 2021-01-15 | — | — | CN | claimed |
| CN-111448520-A | Photoresist stripper composition | 汉高股份有限及两合公司 | 2020-07-24 | — | — | CN | claimed |
| WO-2019199621-A1 | BI-FUNCTIONAL MOLECULES TO DEGRADE CIRCULATING PROTEINS | YALE UNIVERSITY (US) | 2019-10-17 | — | — | WO | claimed |
| EP-1626748-B1 | MOISTURE CURABLE MATERIALS FOR DELIVERY OF AGENTS, METHODS, AND MEDICAL DEVICES | MEDTRONIC INC (US) | 2012-07-11 | — | — | EP | claimed |
| EP-1429763-B1 | NOVEL LIGANDS FOR THE HisB10 Zn2+ SITES OF THE R-STATE INSULIN HEXAMER | NOVO NORDISK AS (DK) | 2007-05-30 | — | — | EP | claimed |
| EP-0646595-B1 | Nucleic acid binding oligomers having C-branches for therapy and diagnosis | BAYER AG (DE) | 1998-11-04 | — | — | EP | claimed |
| EP-0567827-A1 | Process for preparation of N-hydroxyazoles | BASF Aktiengesellschaft (DE) | 1993-11-03 | — | — | EP | claimed |
| EP-0281692-A1 | Additive for lubricants and hydrocarbon fuels comprising reaction products of olefins, sulfur, hydrogen sulfide and nitrogen containing polymeric compounds | MOBIL OIL CORPORATION (US) | 1988-09-14 | — | — | EP | claimed |
| US-4661274-A | Additive for lubricants and hydrocarbon fuels comprising reaction products of olefins, sulfur, hydrogen sulfide and nitrogen containing polymeric compounds | MOBIL OIL CORPORATION (US) | 1987-04-28 | — | — | US | claimed |