SCHEMBL9329936

SCHEMBL9329936

COc1cc(C=CC=CC(=O)O)ccc1O

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.80
CA12 O43570 2/20 0.80
CA1 P00915 2/20 0.80
CA2 P00918 2/20 0.80
CA3 P07451 2/20 0.80
PKM P14618 2/20 0.80
CA4 P22748 2/20 0.80
CA6 P23280 2/20 0.80
CA5A P35218 2/20 0.80
SNCA P37840 2/20 0.80
CA7 P43166 2/20 0.80
CA9 Q16790 2/20 0.80
CA14 Q9ULX7 2/20 0.80
CA5B Q9Y2D0 2/20 0.80
CSNK2A2 P19784 1/20 0.80
CSNK2B P67870 1/20 0.80
CSNK2A1 P68400 1/20 0.80
CSNK2A3 Q8NEV1 1/20 0.80
MAOA P21397 4/20 0.69
MAOB P27338 4/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4651235 1.00 KDM4E (0.80) KDM4ECA12CA1CA2CA3
SCHEMBL23805173 1.00 KDM4E (0.80) KDM4ECA12CA1CA2CA3
SCHEMBL4653690 0.98 KDM4E (0.78) KDM4ECA12CA1CA2CA3
SCHEMBL4653692 0.98 KDM4E (0.78) KDM4ECA12CA1CA2CA3
Ferulate SCHEMBL28912234 0.91 KDM4E (0.97) KDM4ECA12CA1CA2CA3
Ferulate SCHEMBL30880441 0.89 KDM4E (1.00) KDM4ECA12CA1CA2CA3
Ferulate SCHEMBL30760602 0.89 KDM4E (1.00) KDM4ECA12CA1CA2CA3
Ferulate SCHEMBL1908219 0.89 KDM4E (1.00) KDM4ECA12CA1CA2CA3
Ferulate SCHEMBL1703377 0.89 KDM4E (1.00) KDM4ECA12CA1CA2CA3
Ferulate SCHEMBL29365367 0.89 KDM4E (1.00) KDM4ECA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6184054-A None JP disclosed
JP-H06184054-A 5-(4-@(3754/24)ETHOXYCARBONYL)OXY-3-METHOXYPHENYL)-2,4-PENTADIENOIC ACID CHLORIDE AND ITS PRODUCTION HODOGAYA CHEM CO LTD 1994-07-05 JP disclosed
EP-0380669-B1 ISOPRENOID DERIVATIVES AND PHARMACEUTICAL PREPARATION CONTAINING SAME TERUMO CORP (JP) 1994-03-23 EP disclosed
EP-0217271-B1 AMIDE DERIVATIVES AND 5-LYPOXYGENASE INHIBITORS CONTAINING THE SAME TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) 1993-03-17 EP disclosed
EP-0226516-B1 AMIDE DERIVATIVES AND ANTIALLERGIC AGENTS CONTAINING THE SAME TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) 1992-07-29 EP disclosed
US-5130483-A Antiulcer agents and enzyme inhibitors TERUMO KABUSHIKI KAISHA (JP) 1992-07-14 US disclosed
EP-0380669-A1 ISOPRENOID DERIVATIVES AND PHARMACEUTICAL PREPARATION CONTAINING SAME TERUMO KABUSHIKI KAISHA (JP) 1990-08-08 EP disclosed
US-4906631-A Amide derivatives and antiallergic agents containing the same TERUMO KABUSHIKI KAISHA (JP) 1990-03-06 US disclosed
US-4859673-A Amide derivatives and antiallergic agents containing the same TERUMO KABUSHIKI KAISHA (JP) 1989-08-22 US disclosed
US-4816486-A Amide derivatives and 5-lypoxygenase inhibitors containing the same TERUMO CORPORATION (JP) 1989-03-28 US disclosed
US-4795752-A Amide derivatives and antiallergic agents containing the same TERUMO KABUSHIKI KAISHA (JP) 1989-01-03 US disclosed
EP-0244319-A2 Amide derivatives and antiallergic agents containing the same TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) 1987-11-04 EP disclosed
EP-0226516-A2 Amide derivatives and antiallergic agents containing the same TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) 1987-06-24 EP disclosed
EP-0217271-A2 Amide derivatives and 5-lypoxygenase inhibitors containing the same TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) 1987-04-08 EP disclosed