Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | SNCA | P37840 | 2/20 | 0.60 |
| ▸ | FDPS | P14324 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA3 | P07451 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330303 | 1.00 | KDM4E (0.61) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL9329870 | 0.95 | KDM4E (0.53) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL9329877 | 0.95 | KDM4E (0.53) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL7290486 | 0.91 | KDM4E (0.75) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL7290494 | 0.91 | KDM4E (0.75) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL9346642 | 0.89 | KDM4E (0.58) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL10553679 | 0.89 | KDM4E (0.60) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL10553676 | 0.89 | KDM4E (0.60) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL7821694 | 0.87 | KDM4E (0.79) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL6782737 | 0.87 | KDM4E (0.79) | KDM4EALDH1A1HPGDALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0380669-B1 | ISOPRENOID DERIVATIVES AND PHARMACEUTICAL PREPARATION CONTAINING SAME | TERUMO CORP (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-5130483-A | Antiulcer agents and enzyme inhibitors | TERUMO KABUSHIKI KAISHA (JP) | 1992-07-14 | — | — | US | disclosed |
| EP-0380669-A1 | ISOPRENOID DERIVATIVES AND PHARMACEUTICAL PREPARATION CONTAINING SAME | TERUMO KABUSHIKI KAISHA (JP) | 1990-08-08 | — | — | EP | disclosed |