⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3097066 | 0.79 | — | — | |
| SCHEMBL7516446 | 0.79 | — | — | |
| SCHEMBL16280840 | 0.79 | — | — | |
| SCHEMBL429701 | 0.79 | — | — | |
| SCHEMBL13900281 | 0.79 | — | — | |
| SCHEMBL29093226 | 0.79 | — | — | |
| SCHEMBL9160068 | 0.79 | — | — | |
| SCHEMBL13317542 | 0.76 | TSHR (0.44) | — | |
| 3-Pentanol SCHEMBL9668381 | 0.76 | TSHR (0.44) | — | |
| SCHEMBL8653862 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354819-B1 | Novel peptide and anti-dementia agent | NIPPON CHEMIPHAR CO (JP) | 1994-04-13 | — | — | EP | disclosed |
| US-5180712-A | Alzheimer's disease | FUJIREBIO KABUSHIKI KAISHA (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0354819-A2 | Novel peptide and anti-dementia agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |
| EP-0161017-B1 | PEPTIDES | AKZO N.V. (NL) | 1987-06-16 | — | — | EP | disclosed |
| US-4623640-A | Peptides | AKZO N.V. (NL) | 1986-11-18 | — | — | US | disclosed |
| EP-0161017-A1 | Peptides | AKZO N.V. (NL) | 1985-11-13 | — | — | EP | disclosed |