Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.56 |
| ▸ | RARA | P10276 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152815 | 0.96 | PTPN11 (0.62) | RARBPTPN11RARANPC1ALDH1A1 | |
| SCHEMBL8970283 | 0.95 | RARB (0.61) | RARBPTPN11RARANPC1ALDH1A1 | |
| SCHEMBL9735547 | 0.95 | RARB (0.61) | RARBPTPN11RARANPC1ALDH1A1 | |
| SCHEMBL11517805 | 0.88 | PTPN11 (0.65) | RARBPTPN11RARANPC1ALDH1A1 | |
| SCHEMBL11139894 | 0.87 | PTPN11 (0.68) | RARBPTPN11RARANPC1ALDH1A1 | |
| SCHEMBL10593489 | 0.87 | PTPN11 (0.65) | RARBPTPN11RARAMCL1LTA4H | |
| SCHEMBL9485391 | 0.86 | PTPN11 (0.70) | RARBPTPN11RARANPC1ALDH1A1 | |
| SCHEMBL9485471 | 0.86 | PTPN11 (0.70) | RARBPTPN11RARANPC1ALDH1A1 | |
| SCHEMBL7875556 | 0.86 | PTPN11 (0.70) | RARBPTPN11RARANPC1ALDH1A1 | |
| SCHEMBL9486054 | 0.86 | PTPN11 (0.70) | RARBPTPN11RARANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428542-B1 | FERROELECTRIC LIQUID-CRYSTAL POLYMERS CONTAINING Si, PROCESS FOR PRODUCING THE SAME AND THEIR USE IN ELECTRO-OPTICAL ELEMENTS | HOECHST AG (DE) | 1994-09-07 | — | — | EP | disclosed |
| EP-0424461-B1 | Novel ferroelectric liquid-crystal polymers, process for producing said polymers and their use in electro-optical components | HOECHST AG (DE) | 1994-04-13 | — | — | EP | disclosed |
| EP-0424461-A1 | Novel ferroelectric liquid-crystal polymers, process for producing said polymers and their use in electro-optical components. | HOECHST AG (DE) | 1991-05-02 | — | — | EP | disclosed |
| WO-1990000587-A1 | NOVEL FERROELECTRIC LIQUID-CRYSTAL POLYMERS, PROCESS FOR PRODUCING SAID POLYMERS AND THEIR USE IN ELECTRO-OPTICAL COMPONENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-25 | — | — | WO | disclosed |