Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | PPOX | P50336 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751981 | 0.94 | KMT2A (0.47) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL9332065 | 0.84 | MAPT (0.43) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL9332068 | 0.84 | TLR8 (0.44) | NPSR1NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8693593 | 0.83 | MEN1 (0.50) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL10748703 | 0.82 | TDP1 (0.57) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL9331767 | 0.82 | TDP1 (0.47) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL9332431 | 0.81 | KMT2A (0.45) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL10673745 | 0.81 | TDP1 (0.57) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL9134954 | 0.81 | TDP1 (0.50) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL9768748 | 0.80 | TDP1 (0.54) | KMT2AMEN1TDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448206-B1 | Substituted benzimidazole and indazole derivatives, processes for their preparation and their use as herbicides | ZENECA LTD (GB) | 1994-12-28 | — | — | EP | disclosed |
| US-5306692-A | Herbicidal indazole and benzimidazole compounds | ZENECA LIMITED (GB) | 1994-04-26 | — | — | US | disclosed |
| EP-0448206-A2 | Substituted benzimidazole and indazole derivatives, processes for their preparation and their use as herbicides | ZENECA LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |
| CN-1054063-A | Heterogeneous ring compound | ICI PLC (GB) | 1991-08-28 | — | — | CN | disclosed |