SCHEMBL9332247

SCHEMBL9332247

O[C@@H]1C(F)=CC=C(F)[C@@H]1O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9334270 1.00
SCHEMBL9484934 0.79
SCHEMBL9484929 0.79
SCHEMBL22238913 0.64
SCHEMBL2934624 0.54
SCHEMBL13081290 0.50
SCHEMBL6349270 0.50
SCHEMBL14470375 0.50
SCHEMBL18010959 0.49
SCHEMBL28950623 0.49

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0379300-B1 Separation of 1,2-dihydroxycyclohexa-3,5-diene compounds ZENECA LTD (GB) 1994-04-27 EP claimed
US-5105003-A Complexing with phenylboric acid, adjusting ph to precipitate ester, breaking ester IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-04-14 US claimed
EP-0379300-A2 Separation of 1,2-dihydroxycyclohexa-3,5-diene compounds ZENECA LIMITED (GB) 1990-07-25 EP claimed
EP-0379300-B1 Separation of 1,2-dihydroxycyclohexa-3,5-diene compounds ZENECA LTD (GB) 1994-04-27 EP disclosed
US-5105003-A Complexing with phenylboric acid, adjusting ph to precipitate ester, breaking ester IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-04-14 US disclosed
EP-0379300-A2 Separation of 1,2-dihydroxycyclohexa-3,5-diene compounds ZENECA LIMITED (GB) 1990-07-25 EP disclosed