Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 9/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28316555 | 0.74 | CYP2D6 (0.53) | CYP2D6HSD17B10CYP2A6TDP1CYP1A2 | |
| SCHEMBL1048904 | 0.74 | CYP2D6 (0.48) | CYP2D6HSD17B10CYP2A6TDP1CYP1A2 | |
| SCHEMBL26202229 | 0.73 | CYP2D6 (0.47) | CYP2D6HSD17B10CYP2A6TDP1CYP1A2 | |
| SCHEMBL27646855 | 0.73 | CYP2D6 (0.47) | CYP2D6HSD17B10CYP2A6TDP1CYP1A2 | |
| SCHEMBL31094415 | 0.73 | CYP2D6 (0.47) | CYP2D6HSD17B10CYP2A6TDP1CYP1A2 | |
| SCHEMBL638086 | 0.73 | CYP2D6 (0.47) | CYP2D6HSD17B10CYP2A6TDP1CYP1A2 | |
| Iodide SCHEMBL7251052 | 0.73 | CYP2D6 (0.47) | CYP2D6HSD17B10CYP2A6TDP1CYP1A2 | |
| SCHEMBL25672196 | 0.70 | CYP2D6 (0.62) | CYP2D6HSD17B10CYP2A6TDP1CYP1A2 | |
| Bromide SCHEMBL11581318 | 0.68 | CYP2D6 (0.61) | CYP2D6HSD17B10CYP2A6TDP1CYP1A2 | |
| SCHEMBL29518518 | 0.63 | CYP2A6 (0.55) | CYP2A6TDP1CYP1A2NQO1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315997-B1 | Cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA (JP) | 1994-04-20 | — | — | EP | disclosed |
| CN-1022629-C | Process for the preparation of novel cephalosporin compounds | MEIJIE SEIKA KAISHA LTD (JP) | 1993-11-03 | — | — | CN | disclosed |
| US-5028601-A | Substituted with an amino thiazole group and a dihydroxy-pyridone group | MEIJI SAIKA KAISHA, LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| US-4971961-A | ANTIBIOTICS AS BACTERICIDES AGAINST PSEUDOMONAS | MEIJI SEIKA KAISHA, LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0315997-A2 | Cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA LTD. (JP) | 1989-05-17 | — | — | EP | disclosed |
| CN-88102467-A | Process for the preparation of cephalosporin compounds and antibiotics | — | 1988-12-14 | — | — | CN | disclosed |
| EP-0289002-A2 | Novel cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA LTD. (JP) | 1988-11-02 | — | — | EP | disclosed |