Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3926173 | 0.89 | PTPRB (0.78) | PTPRB | |
| SCHEMBL1287189 | 0.89 | PTPRB (0.78) | PTPRB | |
| SCHEMBL933921 | 0.88 | PTPRB (0.79) | PTPRB | |
| SCHEMBL468306 | 0.87 | PTPRB (0.61) | PTPRB | |
| SCHEMBL932526 | 0.87 | PTPRB (0.78) | PTPRB | |
| SCHEMBL1287172 | 0.86 | PTPRB (0.76) | PTPRB | |
| SCHEMBL932727 | 0.86 | PTPRB (0.76) | PTPRB | |
| SCHEMBL3918111 | 0.85 | PTPRB (0.59) | PTPRB | |
| SCHEMBL933887 | 0.85 | PTPRB (0.76) | PTPRB | |
| SCHEMBL3920078 | 0.85 | PTPRB (0.77) | PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451279-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR PREVENTING METASTASIS OF CANCER CELLS | Akebia Therapeutics Inc. (US) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011005330-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR PREVENTING METASTASIS OF CANCER CELLS | AKEBIA THERAPEUTICS INC. (US) | 2011-01-13 | — | — | WO | disclosed |
| EP-2038265-A2 | HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE | The Procter and Gamble Company (US) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008002570-A2 | HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-03 | — | — | WO | disclosed |