Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.74 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.65 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.62 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7931743 | 0.88 | DYRK1A (0.72) | DYRK1ADUSP3CHRM4KMT2AMEN1 | |
| SCHEMBL8350097 | 0.88 | DYRK1A (0.72) | DYRK1ADUSP3CHRM4KMT2AMEN1 | |
| SCHEMBL9332428 | 0.85 | DYRK1A (0.71) | DYRK1ADUSP3CHRM4KMT2AMEN1 | |
| SCHEMBL15376502 | 0.85 | DYRK1A (1.00) | DYRK1ADUSP3CHRM4KMT2AMEN1 | |
| SCHEMBL20660046 | 0.85 | DYRK1A (0.80) | DYRK1ADUSP3CHRM4KMT2AMEN1 | |
| SCHEMBL3047328 | 0.85 | DYRK1A (0.80) | DYRK1ADUSP3CHRM4KMT2AMEN1 | |
| Hydrazine SCHEMBL20659924 | 0.84 | DYRK1A (0.74) | DYRK1ADUSP3CHRM4KMT2AMEN1 | |
| SCHEMBL3050805 | 0.84 | DYRK1A (0.78) | DYRK1ADUSP3CHRM4KMT2AMEN1 | |
| SCHEMBL20659925 | 0.83 | DYRK1A (0.76) | DYRK1ADUSP3CHRM4KMT2AMEN1 | |
| SCHEMBL22374141 | 0.82 | DYRK1A (0.74) | DYRK1ADUSP3CHRM4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397169-B1 | Novel benzothiazole derivatives | TOYO BOSEKI (JP) | 1994-04-13 | — | — | EP | claimed |
| US-5036086-A | Novel benzothiazole derivatives | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-07-30 | — | — | US | claimed |
| EP-0397169-A1 | Novel benzothiazole derivatives | TOYO BOSEKI KABUSHIKI KAISHA Trading under the name of Toyobo Co., Ltd. (JP) | 1990-11-14 | — | — | EP | claimed |
| EP-0397169-B1 | Novel benzothiazole derivatives | TOYO BOSEKI (JP) | 1994-04-13 | — | — | EP | disclosed |
| US-5036086-A | Novel benzothiazole derivatives | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-07-30 | — | — | US | disclosed |
| EP-0397169-A1 | Novel benzothiazole derivatives | TOYO BOSEKI KABUSHIKI KAISHA Trading under the name of Toyobo Co., Ltd. (JP) | 1990-11-14 | — | — | EP | disclosed |