Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333038 | 0.95 | HSD17B10 (0.63) | HSD17B10TSHRCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9333000 | 0.94 | HSD17B10 (0.47) | HSD17B10TSHRCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9335411 | 0.93 | HSD17B10 (0.66) | HSD17B10TSHRCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9335482 | 0.93 | HSD17B10 (0.66) | HSD17B10TSHRCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9335275 | 0.93 | HSD17B10 (0.66) | HSD17B10TSHRCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL10992456 | 0.93 | HSD17B10 (0.65) | HSD17B10TSHRCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL28255947 | 0.93 | HSD17B10 (0.62) | HSD17B10TSHRRARBALDH1A1MEN1 | |
| SCHEMBL9333020 | 0.89 | CYP1A1 (0.53) | HSD17B10TSHRCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9335457 | 0.89 | HSD17B10 (0.54) | HSD17B10TSHRRARBALDH1A1MEN1 | |
| SCHEMBL9333518 | 0.87 | HSD17B10 (0.57) | HSD17B10TSHRALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377516-B1 | Liquid crystal compounds having high optical anisotropy | CHISSO CORP (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5154851-A | LIQUID CRYSTAL COMPOUND HAVING LARGE OPTICAL ANISOTROPY VALUE | CHISSO CORPORATION (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0377516-A2 | Liquid crystal compounds having high optical anisotropy | Chisso Corporation (JP) | 1990-07-11 | — | — | EP | disclosed |