Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 7/20 | 0.79 |
| ▸ | SRD5A2 | P31213 | 7/20 | 0.79 |
| ▸ | CNR2 | P34972 | 9/20 | 0.51 |
| ▸ | CNR1 | P21554 | 6/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | GCG | P01275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432773 | 1.00 | SRD5A1 (0.79) | SRD5A1SRD5A2CNR2CNR1ADRA1D | |
| SCHEMBL9334029 | 1.00 | SRD5A1 (0.79) | SRD5A1SRD5A2CNR2CNR1ADRA1D | |
| SCHEMBL9334061 | 0.98 | SRD5A1 (0.78) | SRD5A1SRD5A2CNR2CNR1ADRA1D | |
| SCHEMBL9337524 | 0.97 | SRD5A1 (0.77) | SRD5A1SRD5A2CNR2CNR1ADRA1D | |
| SCHEMBL9334526 | 0.97 | SRD5A1 (0.77) | SRD5A1SRD5A2CNR2CNR1ADRA1D | |
| SCHEMBL9441212 | 0.96 | SRD5A1 (0.80) | SRD5A1SRD5A2CNR2CNR1ADRA1D | |
| SCHEMBL9334465 | 0.96 | SRD5A1 (0.80) | SRD5A1SRD5A2CNR2CNR1ADRA1D | |
| SCHEMBL9441222 | 0.96 | SRD5A1 (0.80) | SRD5A1SRD5A2CNR2CNR1ADRA1D | |
| SCHEMBL9441229 | 0.93 | SRD5A1 (0.83) | SRD5A1SRD5A2CNR2CNR1ADRA1D | |
| SCHEMBL9441204 | 0.93 | SRD5A1 (0.83) | SRD5A1SRD5A2CNR2CNR1ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312829-A | Testosterone 5alpha-reductase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-17 | — | — | US | claimed |
| EP-0603278-A1 | INDOLE DERIVATIVES AS 5-ALPHA-REDUCTASE INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5312829-A | Testosterone 5alpha-reductase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| WO-1993005019-A1 | INDOLE DERIVATIVES AS 5-ALPHA-REDUCTASE INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-18 | — | — | WO | disclosed |