Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.37 |
| ▸ | RELA | Q04206 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335581 | 0.86 | RARB (0.39) | SMN1; SMN2RAB9ANPC1TP53PKM | |
| SCHEMBL9334037 | 0.85 | CYP1A1 (0.41) | SMN1; SMN2RAB9ANPC1TP53PKM | |
| SCHEMBL10462529 | 0.85 | SMN1; SMN2 (0.63) | SMN1; SMN2RAB9ANPC1TP53PKM | |
| SCHEMBL10462605 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9ANPC1TP53PKM | |
| SCHEMBL10463006 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9ANPC1TP53PKM | |
| SCHEMBL9334142 | 0.80 | GRM5 (0.38) | SMN1; SMN2RAB9ANPC1TP53PKM | |
| SCHEMBL9337254 | 0.80 | RARB (0.43) | SMN1; SMN2RAB9ANPC1TP53PKM | |
| SCHEMBL10461961 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9ANPC1TP53PKM | |
| SCHEMBL10460928 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9ANPC1TP53PKM | |
| SCHEMBL9337526 | 0.79 | RARB (0.42) | SMN1; SMN2RAB9ANPC1TP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328637-A | Electrooptical devices; deformation of aligned phases and supertwisted nematic applications; miscibility, solubility | HOFFMANN-LA ROCHE INC. (US) | 1994-07-12 | — | — | US | disclosed |