Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 5/20 | 0.68 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.68 |
| ▸ | CNR1 | P21554 | 9/20 | 0.50 |
| ▸ | CNR2 | P34972 | 8/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337602 | 0.98 | SRD5A1 (0.69) | SRD5A1SRD5A2CNR1CNR2POLB | |
| SCHEMBL9334514 | 0.96 | SRD5A1 (0.70) | SRD5A1SRD5A2CNR1CNR2POLB | |
| SCHEMBL9337667 | 0.93 | SRD5A1 (0.72) | SRD5A1SRD5A2CNR1CNR2POLB | |
| SCHEMBL9334133 | 0.91 | SRD5A1 (0.81) | SRD5A1SRD5A2CNR1CNR2 | |
| SCHEMBL8794320 | 0.91 | SRD5A1 (0.81) | SRD5A1SRD5A2CNR1CNR2POLB | |
| SCHEMBL9335527 | 0.89 | SRD5A1 (0.83) | SRD5A1SRD5A2CNR1CNR2 | |
| SCHEMBL8793720 | 0.89 | SRD5A1 (0.78) | SRD5A1SRD5A2CNR1CNR2POLB | |
| SCHEMBL9337850 | 0.88 | SRD5A1 (0.71) | SRD5A1SRD5A2CNR1CNR2POLB | |
| SCHEMBL9337867 | 0.87 | SRD5A1 (0.84) | SRD5A1SRD5A2CNR1CNR2 | |
| SCHEMBL8793415 | 0.87 | SRD5A1 (0.76) | SRD5A1SRD5A2CNR1CNR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603278-A1 | INDOLE DERIVATIVES AS 5-ALPHA-REDUCTASE INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5312829-A | Testosterone 5alpha-reductase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| US-5212320-A | Enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-18 | — | — | US | disclosed |
| WO-1993005019-A1 | INDOLE DERIVATIVES AS 5-ALPHA-REDUCTASE INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-18 | — | — | WO | disclosed |