Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA4 | P22748 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28750843 | 1.00 | CA12 (0.43) | CA12CA1CA2CA4CA9 | |
| SCHEMBL3402931 | 1.00 | CA12 (0.43) | CA12CA1CA2CA4CA9 | |
| SCHEMBL3993199 | 1.00 | CA12 (0.43) | CA12CA1CA2CA4CA9 | |
| SCHEMBL3990507 | 0.98 | — | — | |
| SCHEMBL1041500 | 0.90 | — | — | |
| SCHEMBL25180667 | 0.87 | CA12 (0.50) | CA12CA1CA2CA4CA9 | |
| SCHEMBL324868 | 0.87 | CA12 (0.50) | CA12CA1CA2CA4CA9 | |
| SCHEMBL25180691 | 0.87 | CA12 (0.50) | CA12CA1CA2CA4CA9 | |
| SCHEMBL8957343 | 0.87 | CA12 (0.50) | CA12CA1CA2CA4CA9 | |
| SCHEMBL1842696 | 0.87 | CA12 (0.50) | CA12CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361888-B1 | Apovincaminic acid derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-4980474-A | For treatment of vascular injuries, angina pectoris, hypertension and alzheimer*s disease | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1990-12-25 | — | — | US | disclosed |
| EP-0361888-A2 | Apovincaminic acid derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1990-04-04 | — | — | EP | disclosed |