Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.66 |
| ▸ | MAOB | P27338 | 8/20 | 0.58 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339227 | 0.81 | PTGER4 (0.58) | PTGER4CYSLTR1CYSLTR2NPC1RAB9A | |
| SCHEMBL9754811 | 0.80 | NPC1 (0.55) | PTGER4CYSLTR1CYSLTR2NPC1RAB9A | |
| SCHEMBL9335208 | 0.80 | NPC1 (0.55) | PTGER4MAOBCYSLTR1CYSLTR2NPC1 | |
| SCHEMBL9334993 | 0.80 | PTGER4 (0.53) | PTGER4MAOBCYSLTR1CYSLTR2NPC1 | |
| SCHEMBL9339025 | 0.80 | PTGER4 (0.53) | PTGER4CYSLTR1CYSLTR2NPC1RAB9A | |
| SCHEMBL9336045 | 0.80 | PTGER4 (0.55) | PTGER4CYSLTR1CYSLTR2NPC1RAB9A | |
| SCHEMBL9339029 | 0.80 | PTGER4 (0.55) | PTGER4MAOBCYSLTR1CYSLTR2NPC1 | |
| SCHEMBL9335413 | 0.79 | PTGER4 (0.55) | PTGER4CYSLTR1CYSLTR2NPC1RAB9A | |
| SCHEMBL9335426 | 0.79 | PTGER4 (0.55) | PTGER4CYSLTR1CYSLTR2NPC1RAB9A | |
| SCHEMBL28805886 | 0.78 | PTGER4 (0.58) | PTGER4MAOBNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533695-B1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER (US) | 1994-10-05 | — | — | EP | disclosed |
| US-5322847-A | Inhibit platelet activating factor, block leukotriene D4 receptors | PFIZER INC. (US) | 1994-06-21 | — | — | US | disclosed |