Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.51 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.51 |
| ▸ | TLR2 | O60603 | 9/20 | 0.48 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30826314 | 0.91 | LPAR1 (0.59) | HTTLPAR1LPAR3TLR2LPAR2 | |
| SCHEMBL6914851 | 0.88 | LPAR1 (0.47) | LPAR1LPAR3TLR2LPAR2TSHR | |
| SCHEMBL3243893 | 0.87 | MEN1 (0.42) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL11313784 | 0.85 | MAPT (0.50) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL6247348 | 0.84 | HTT (0.64) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL8090207 | 0.84 | LPAR1 (0.50) | MEN1KMT2AMAPTLPAR1LPAR3 | |
| SCHEMBL10558616 | 0.83 | HTT (0.69) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL30381832 | 0.82 | LPAR1 (0.47) | LPAR1LPAR3TLR2LPAR2PLA2G2C | |
| SCHEMBL30965420 | 0.81 | HTT (0.67) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL8505229 | 0.81 | HTT (0.67) | MEN1THRBHTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300149-A | Fluid flow mixtures consists of reduced water is hardened to form weatherproofing structures; workability, strength, freeze resistance | THE LUBRIZOL CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| EP-0561627-A1 | Cementitious compositions | The Lubrizol Corporation (US) | 1993-09-22 | — | — | EP | disclosed |