Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368344 | 1.00 | CYP2C19 (0.36) | CYP2C19MME | |
| SCHEMBL9341047 | 1.00 | CYP2C19 (0.36) | CYP2C19MME | |
| SCHEMBL7296981 | 0.98 | CYP2C19 (0.35) | CYP2C19MME | |
| SCHEMBL7131535 | 0.85 | MME (0.37) | CYP2C19MME | |
| SCHEMBL7296971 | 0.85 | — | — | |
| SCHEMBL7300805 | 0.83 | CYP2C19 (0.37) | CYP2C19 | |
| SCHEMBL5702723 | 0.83 | MME (0.41) | CYP2C19MME | |
| SCHEMBL5702726 | 0.83 | MME (0.41) | CYP2C19MME | |
| SCHEMBL9469991 | 0.83 | MEN1 (0.33) | CYP2C19MME | |
| SCHEMBL5924834 | 0.83 | CYP2C19 (0.33) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5362902-A | Diuretics and treatment of cardiovascular disorders | PFIZER INC. (US) | 1994-11-08 | — | — | US | disclosed |
| EP-0432898-B1 | Glutaric acid derivatives and preparation thereof | PFIZER LTD (GB) | 1994-04-13 | — | — | EP | disclosed |
| US-5260467-A | Glutaric acid derivatives and preparation thereof | PFIZER INC. (US) | 1993-11-09 | — | — | US | disclosed |
| US-5157138-A | Glutaric acid derivatives and preparation thereof | PFIZER, INC. (US) | 1992-10-20 | — | — | US | disclosed |
| US-5087732-A | GLUTARIC ACID DERIVATIVES AND PREPARATION THEREOF | PFIZER INC. (US) | 1992-02-11 | — | — | US | disclosed |
| EP-0432898-A2 | Glutaric acid derivatives and preparation thereof | Pfizer Limited (GB) | 1991-06-19 | — | — | EP | disclosed |
| WO-1991008195-A1 | N-(1-(2-CARBOXYETHYL)CYCLOALKYL CARBONYL)-BETA-ALANINE DERIVATIVES FOR PHARMACEUTICAL USE | PFIZER LIMITED (GB) | 1991-06-13 | — | — | WO | disclosed |